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Heterosynaptic eLTD occurs at synapses adjacent towards the stimulated synapses. Such as, stimulation of Schaffer collaterals in hippocampal CA1 contributes to a persistent minimize in GABAergic inhibition of CA1 pyramidal neurons (106). The mechanism of eLTD at hippocampal inhibitory synapses seems to need inhibition of adenylyl cyclase and the in